Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456869 | 0.81 | CA1 (0.55) | GSK3BKMT2AMAPTMEN1LMNA | |
| SCHEMBL1154812 | 0.78 | GSK3B (0.57) | GSK3BKMT2AL3MBTL1MAPTHPGD | |
| SCHEMBL9257364 | 0.76 | LMNA (0.50) | GSK3BKMT2AL3MBTL1MAPTHPGD | |
| SCHEMBL31324508 | 0.75 | IDO1 (0.50) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL15227042 | 0.73 | NPC1 (0.50) | L3MBTL1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL1155397 | 0.72 | GSK3B (0.50) | GSK3BKMT2AL3MBTL1MAPTHPGD | |
| SCHEMBL1155564 | 0.72 | ALDH1A1 (0.62) | GSK3BKMT2AL3MBTL1MAPTHPGD | |
| SCHEMBL28841619 | 0.71 | MMP1 (0.56) | GSK3BKMT2AL3MBTL1MAPTHPGD | |
| SCHEMBL4452972 | 0.71 | CA1 (0.62) | GSK3BKMT2AMAPTMEN1RAB9A | |
| SCHEMBL2773681 | 0.71 | MAPT (0.52) | GSK3BKMT2AL3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389162-B1 | 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0389162-A1 | 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1990-09-26 | — | — | EP | disclosed |