Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547975 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL10430643 | 0.85 | PTGS2 (0.48) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL9548044 | 0.81 | PTGS2 (0.72) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL10430827 | 0.80 | PTGS2 (0.42) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL7843171 | 0.77 | PTGS2 (0.48) | PTGS2PTGS1MAPK13MAPK12MAPK11 | |
| SCHEMBL9548013 | 0.72 | PTGS2 (0.71) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL7847052 | 0.70 | PTGDR2 (0.51) | PTGS2PTGS1MAPK14 | |
| SCHEMBL7833390 | 0.68 | PTGS2 (0.62) | PTGS2PTGS1KDM4EMAPK13MAPK12 | |
| SCHEMBL7844983 | 0.68 | PTGS2 (0.62) | PTGS2PTGS1KDM4EMAPK13MAPK12 | |
| SCHEMBL9617494 | 0.67 | PTGS2 (0.47) | PTGS2PTGS1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217971-A | Anticoagulants, hypotensive agents, antiallergens and antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |