Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755257 | 0.75 | SLC6A3 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8935940 | 0.71 | LTA4H (0.46) | SLC6A2SLC6A4SLC6A3BCHEACHE | |
| SCHEMBL9548162 | 0.69 | LTA4H (0.39) | SLC6A2SLC6A4SLC6A3BCHEACHE | |
| SCHEMBL2350562 | 0.68 | CTSD (0.38) | SLC6A2SLC6A4SLC6A3OGAHTT | |
| SCHEMBL2350556 | 0.68 | CTSD (0.38) | SLC6A2SLC6A4SLC6A3OGAHTT | |
| SCHEMBL27791726 | 0.68 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3OGAHTT | |
| SCHEMBL27791725 | 0.68 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3OGAHTT | |
| SCHEMBL30014861 | 0.68 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR2COGA | |
| SCHEMBL4839653 | 0.68 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL8588353 | 0.67 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3OGAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198208-A | Chelate compounds for diagnosis by magnetic resonance imaging, ultrasound or radiation therapy | NYCOMED IMAGING AS (NO) | 1993-03-30 | — | — | US | disclosed |