Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456082 | 0.80 | LMNA (0.69) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL14382350 | 0.78 | GLA (0.63) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL27831488 | 0.74 | LMNA (0.56) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL25765152 | 0.73 | ALDH1A1 (0.57) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL23220249 | 0.73 | THRB (0.63) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL2841738 | 0.73 | THRB (0.63) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL16064957 | 0.72 | HTT (0.54) | LMNAGLAALDH1A1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL28131943 | 0.71 | THRB (0.61) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL19006938 | 0.70 | LMNA (0.49) | LMNAGLAALDH1A1HTTCRHBP | |
| SCHEMBL27444946 | 0.70 | ALDH1A1 (0.58) | LMNAGLAALDH1A1HTTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347216-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYLHYDRAZINES AND N'-SUBSTITUTED -N-ACYL-N'-ALKYLCARBONYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| EP-0347216-A2 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acylhydrazines and N'-substituted -N-acyl-N'-alkylcarbonyl hydrazines | ROHM AND HAAS COMPANY (US) | 1989-12-20 | — | — | EP | disclosed |