Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755899 | 0.75 | FFAR4 (0.38) | FFAR4NPSR1KDM4EHSD17B10 | |
| SCHEMBL18513549 | 0.65 | NPSR1 (0.45) | NPSR1KDM4EHSD17B10 | |
| SCHEMBL28830916 | 0.61 | NPSR1 (0.50) | NPSR1KDM4EHSD17B10 | |
| SCHEMBL314801 | 0.61 | MEN1 (0.45) | NPSR1KDM4EHSD17B10 | |
| SCHEMBL17755880 | 0.61 | MITF (0.38) | FFAR4NPSR1 | |
| SCHEMBL9666458 | 0.60 | PPARA (0.51) | NPSR1 | |
| SCHEMBL4437207 | 0.60 | NPSR1 (0.41) | FFAR4NPSR1KDM4EHSD17B10 | |
| SCHEMBL2919515 | 0.60 | NPSR1 (0.48) | NPSR1KDM4EHSD17B10 | |
| SCHEMBL364082 | 0.58 | NPSR1 (0.46) | NPSR1KDM4EHSD17B10 | |
| SCHEMBL29115321 | 0.58 | LMNA (0.50) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | claimed |
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |