Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658761 | 0.84 | HPGD (0.42) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL8342120 | 0.76 | LMNA (0.47) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL22645203 | 0.76 | LMNA (0.47) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL7591398 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL11778450 | 0.76 | LMNA (0.48) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL11285322 | 0.75 | LMNA (0.46) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL708587 | 0.75 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL20471861 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL7595426 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL9816383 | 0.72 | LMNA (0.53) | ALDH1A1SMN1; SMN2HPGDRAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010825-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0504266-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1992-09-23 | — | — | EP | disclosed |
| WO-1991009007-A2 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1991-06-27 | — | — | WO | disclosed |