Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548413 | 1.00 | ELANE (0.38) | ELANEFABP7FABP5F10MEN1 | |
| SCHEMBL10590411 | 1.00 | ELANE (0.38) | ELANEFABP7FABP5F10MEN1 | |
| SCHEMBL10590408 | 0.90 | ELANE (0.39) | ELANEFABP7FABP5F10MEN1 | |
| SCHEMBL9548494 | 0.90 | ELANE (0.39) | ELANEFABP7FABP5F10MEN1 | |
| SCHEMBL9548492 | 0.90 | ELANE (0.39) | ELANEFABP7FABP5F10MEN1 | |
| SCHEMBL8825898 | 0.74 | ELANE (0.48) | ELANEFABP7FABP5MEN1KMT2A | |
| SCHEMBL7806835 | 0.74 | ELANE (0.48) | ELANEFABP7FABP5MEN1KMT2A | |
| SCHEMBL9548487 | 0.72 | ELANE (0.44) | ELANEF10TBXAS1 | |
| SCHEMBL9548455 | 0.67 | ELANE (0.42) | ELANEF10KMT2AALDH1A1TBXAS1 | |
| SCHEMBL9548456 | 0.65 | ELANE (0.38) | ELANEF10KMT2AALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336143-B1 | A NEW PROCESS FOR CARBAPENEM INTERMEDIATES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4960879-A | REACTING SUBSTITUTED AZETIDINONE WITH TRANS SUBSTITUTED-METHYL ALKYLACRYLIC ACID AND REDUCING METAL | SHIONOGI & CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0336143-A1 | A new process for carbapenem intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |