Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548492 | 1.00 | ELANE (0.39) | ELANEFABP7FABP5F10SMN1; SMN2 | |
| SCHEMBL10590408 | 1.00 | ELANE (0.39) | ELANEFABP7FABP5F10SMN1; SMN2 | |
| SCHEMBL10590411 | 0.90 | ELANE (0.38) | ELANEFABP7FABP5F10SMN1; SMN2 | |
| SCHEMBL9548413 | 0.90 | ELANE (0.38) | ELANEFABP7FABP5F10SMN1; SMN2 | |
| SCHEMBL9548416 | 0.90 | ELANE (0.38) | ELANEFABP7FABP5F10SMN1; SMN2 | |
| SCHEMBL7806835 | 0.81 | ELANE (0.48) | ELANEFABP7FABP5MEN1KMT2A | |
| SCHEMBL8825898 | 0.81 | ELANE (0.48) | ELANEFABP7FABP5MEN1KMT2A | |
| SCHEMBL9548455 | 0.72 | ELANE (0.42) | ELANEF10KMT2ALMNA | |
| SCHEMBL10758551 | 0.69 | ELANE (0.48) | ELANE | |
| SCHEMBL6893609 | 0.69 | ELANE (0.48) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336143-B1 | A NEW PROCESS FOR CARBAPENEM INTERMEDIATES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4960879-A | REACTING SUBSTITUTED AZETIDINONE WITH TRANS SUBSTITUTED-METHYL ALKYLACRYLIC ACID AND REDUCING METAL | SHIONOGI & CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0336143-A1 | A new process for carbapenem intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |