Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548751 | 0.91 | ADORA3 (0.40) | ADORA3PNPBLMUSP2TSHR | |
| SCHEMBL9548605 | 0.86 | ADORA3 (0.42) | ADORA3PNPBLMUSP2TSHR | |
| SCHEMBL9548775 | 0.86 | ADORA3 (0.44) | ADORA3PNPBLMUSP2TSHR | |
| SCHEMBL9548845 | 0.83 | ADORA3 (0.42) | ADORA3PNPBLMUSP2TSHR | |
| SCHEMBL9548762 | 0.81 | ADORA3 (0.40) | ADORA3PNPBLMUSP2TSHR | |
| SCHEMBL9548697 | 0.80 | PDE4D (0.31) | — | |
| SCHEMBL9548787 | 0.79 | DUT (0.31) | — | |
| SCHEMBL9548906 | 0.78 | TK1 (0.32) | TK1ALDH1A1 | |
| SCHEMBL9548623 | 0.77 | ADORA3 (0.40) | ADORA3PNPBLMUSP2TSHR | |
| SCHEMBL9548670 | 0.77 | MEN1 (0.35) | ADORA3PNPBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |