Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220646 | 0.80 | PTGDR2 (0.50) | FASNKMT2APTGDR2PDK2 | |
| SCHEMBL3911363 | 0.75 | GAA (0.47) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL5517055 | 0.73 | GAA (0.49) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL20542375 | 0.72 | GAA (0.51) | KDM4EKMT2ALMNA | |
| SCHEMBL9548910 | 0.72 | NAMPT (0.40) | ADRB3FASNMAPTBRD4 | |
| SCHEMBL28421308 | 0.71 | CAMKK2 (0.47) | NUDT1BACE1 | |
| SCHEMBL5509735 | 0.71 | PDK2 (0.41) | FASNKDM4EMAPTPDK2 | |
| SCHEMBL349054 | 0.70 | CYP4F2 (0.45) | KDM4EMAPT | |
| SCHEMBL3963722 | 0.69 | HDAC6 (0.46) | NUDT1BACE1KDM4ELMNA | |
| SCHEMBL7443727 | 0.69 | KDM4E (0.49) | NUDT1BACE1FASNKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543858-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |