Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | HINT1 | P49773 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548788 | 0.90 | AHCY (0.41) | AHCYPNPLMNATP53HTT | |
| SCHEMBL9548729 | 0.90 | ADA (0.43) | AHCYTP53SMN1; SMN2ADORA2AADORA3 | |
| SCHEMBL9548709 | 0.90 | ADA (0.43) | AHCYTP53SMN1; SMN2ADORA2AADORA3 | |
| SCHEMBL9548649 | 0.86 | ADORA3 (0.43) | PNPPDE3AHINT1NT5EADORA3 | |
| SCHEMBL9548660 | 0.86 | ADORA3 (0.43) | PNPPDE3AHINT1NT5EADORA3 | |
| SCHEMBL9548650 | 0.85 | AHCY (0.44) | AHCYPNPLMNATP53HTT | |
| SCHEMBL9548797 | 0.85 | AHCY (0.44) | AHCYPNPLMNATP53HTT | |
| SCHEMBL9548908 | 0.85 | AHCY (0.44) | AHCYPNPLMNATP53HTT | |
| SCHEMBL9548798 | 0.83 | ALDH1A1 (0.45) | LMNAADORA3 | |
| SCHEMBL9548627 | 0.82 | AHCY (0.42) | AHCYPNPLMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |