SCHEMBL9549005

SCHEMBL9549005

COc1cc2cnncc2cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
NQO2 P16083 1/20 0.44
PDGFRB P09619 10/20 0.43
PDGFRA P16234 10/20 0.43
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
EHMT2 Q96KQ7 1/20 0.40
SOS1 Q07889 1/20 0.40
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11496731 0.78 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2KDM4EPDE4APDE4B
SCHEMBL27765191 0.76 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2KDM4EPDE4APDE4B
SCHEMBL2138144 0.76 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2KDM4EPDE4APDE4B
SCHEMBL29027368 0.76 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2KDM4ENQO2MAPT
SCHEMBL31678471 0.74 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTGAASOS1
SCHEMBL3783978 0.74 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2KDM4EPDE4APDE4B
SCHEMBL1271246 0.74 MAOA (0.59) ALDH1A1SMN1; SMN2KDM4EPDGFRBPDGFRA
SCHEMBL4157998 0.73 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2KDM4EPDE4APDE4B
SCHEMBL29945866 0.73 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2KDM4EPDE4APDE4B
SCHEMBL29945742 0.73 ALDH1A1 (0.55) ALDH1A1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070224554-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2007-09-27 US disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7223531-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2007-05-29 US disclosed
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 US disclosed
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 US disclosed
US-20070003884-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 2007-01-04 US disclosed
US-5194433-A Improved effectiveness against resistant bacteria BRISTOL-MYERS SQUIBB COMPANY (US) 1993-03-16 US disclosed
EP-0485808-A2 Antibiotic C-3 catechol-substituted cephalosporin compounds, compositions and use thereof Bristol-Myers Squibb Company (US) 1992-05-20 EP disclosed