SCHEMBL9549156

SCHEMBL9549156

Cc1ccccc1N(C)Cl

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ACHE P22303 2/20 0.45
SIGMAR1 Q99720 1/20 0.41
LMNA P02545 2/20 0.40
CYP3A4 P08684 2/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
ALDH1A1 P00352 6/20 0.39
TP53 P04637 2/20 0.39
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
C5AR1 P21730 1/20 0.38
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3840747 0.81 TSHR (0.47) TSHRACHESIGMAR1LMNACYP3A4
SCHEMBL2620728 0.78 ACHE (0.50) TSHRACHESIGMAR1LMNACYP3A4
SCHEMBL29435133 0.78 TSHR (0.50) TSHRACHESIGMAR1LMNACYP3A4
SCHEMBL29239 0.78 TSHR (0.50) TSHRACHESIGMAR1LMNACYP3A4
SCHEMBL7932525 0.77 ACHE (0.43) TSHRACHESIGMAR1LMNACYP3A4
SCHEMBL5032969 0.77 LMNA (0.44) TSHRSIGMAR1LMNACYP3A4TRPM8
Lithium Ion SCHEMBL19732623 0.76 TSHR (0.47) TSHRACHESIGMAR1LMNACYP3A4
SCHEMBL21065735 0.76 TSHR (0.47) TSHRACHESIGMAR1LMNACYP3A4
Hydrochloric Acid SCHEMBL6421167 0.76 TSHR (0.47) TSHRACHESIGMAR1LMNACYP3A4
Hydrochloric Acid SCHEMBL2869837 0.76 TSHR (0.47) TSHRACHESIGMAR1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024177858-A1 PROCESSES FOR REDUCING ENVIRONMENTAL AVAILABILITY OF ENVIRONMENTAL POLLUTANTS ALBEMARLE CORPORATION (US) 2024-08-29 WO disclosed
EP-0288515-B1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS ISP INVESTMENTS INC. (US) 1993-05-05 EP disclosed
EP-0288515-A4 QUATERNIZED NITROGEN CONTAINING COMPOUNDS 1990-09-26 EP disclosed
US-4834970-A Cosometic compositions containing quaternized nitrogen containing compound GAF CORPORATION (US) 1989-05-30 US disclosed
EP-0288515-A1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS. GAF CORP (US) 1988-11-02 EP disclosed
WO-1988002985-A1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS GAF CORPORATION (US) 1988-05-05 WO disclosed
EP-0252603-A2 Adhesives for ceramics and processes for the bonding of ceramics using same MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-01-13 EP disclosed
US-4096139-A Azocoumarinic-type dyes for the disperse dyeing of textile fabrics MONTEDISON S.P.A. (IT) 1978-06-20 US disclosed