Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549343 | 0.81 | KMT2A (0.49) | HTR2AHTR2CHTR2BMAOBSLC6A2 | |
| SCHEMBL9549529 | 0.67 | CA1 (0.33) | — | |
| SCHEMBL8256334 | 0.64 | KDM4E (0.51) | HTR2AMAOBSLC6A2KDM4EPKM | |
| Hydrochloric Acid SCHEMBL11776858 | 0.63 | KDM4E (0.50) | HTR2AHTR2CKDM4EPKM | |
| SCHEMBL11674535 | 0.62 | KDM1A (0.36) | HTR2AHTR2CHTR2BMAOBKMT2A | |
| SCHEMBL9543103 | 0.61 | SLC6A2 (0.49) | HTR2AHTR2CHTR2BMAOBSLC6A2 | |
| SCHEMBL10919330 | 0.60 | KDM4E (0.39) | HTR2AMAOBKDM4EPKM | |
| SCHEMBL8200284 | 0.60 | MAPK1 (0.47) | HTR2AHTR2CHTR2BKDM4EPKM | |
| SCHEMBL2826156 | 0.59 | MAPT (0.42) | HTR2AHTR2CHTR2BKDM4EPKM | |
| SCHEMBL1651970 | 0.59 | MAPT (0.42) | HTR2AHTR2CHTR2BKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219839-A | Analgesics; anticonvulsant and -epileptic agents; antidepressants; anxiolytic, antiarrhythmic and hypotensive agents; anticoagulants | LABORATORIES UPSA (FR) | 1993-06-15 | — | — | US | disclosed |