SCHEMBL9549356

SCHEMBL9549356

CC1(CO)C=Cc2ccccc2C1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
XDH P47989 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
PARP1 P09874 1/20 0.32
HTR2A P28223 1/20 0.31
BRD4 O60885 1/20 0.31
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4679449 0.80 HSD11B1 (0.36)
SCHEMBL9649135 0.77 ALDH1A1 (0.40)
SCHEMBL19249294 0.76 CA1 (0.31) CA1CA2
SCHEMBL23781284 0.76 PARP1 (0.34) CA1CA2PARP1MAOB
SCHEMBL1697644 0.75 PARP1 (0.36) CA1CA2PARP1HTR2AMAOB
SCHEMBL5133900 0.72 PARP1 (0.34) CA1CA2PARP1MAOB
SCHEMBL25680741 0.72 MAOB (0.36) CA1CA2PARP1HTR2AMAOB
SCHEMBL13816705 0.72 PARP1 (0.34) CA1CA2PARP1MAOB
SCHEMBL10339778 0.71 ALDH1A1 (0.40)
SCHEMBL258234 0.71 PARP1 (0.36) CA1CA2PARP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5191133-A PROCESS FOR PREPARATION OF 2-VINYLNAPHTHALENE HOESCHT CELANESE CORPORATION (US) 1993-03-02 US disclosed