SCHEMBL115377

SCHEMBL115377

CCCCCCCCCCCCCCCCCCOCCCN(CC)CC

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.50
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
CES2 O00748 1/20 0.42
PLA2G1B P04054 1/20 0.41
PLA2G2A P14555 1/20 0.41
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.39
USP2 O75604 1/20 0.39
TSHR P16473 1/20 0.39
SPHK1 Q9NYA1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9807805 1.00 MEN1 (0.50) MEN1THRBHTTKMT2AMAPT
SCHEMBL28138868 1.00 MEN1 (0.50) MEN1THRBHTTKMT2AMAPT
SCHEMBL5162321 1.00 MEN1 (0.50) MEN1THRBHTTKMT2AMAPT
SCHEMBL24688603 0.98 MEN1 (0.46) MEN1THRBHTTKMT2AMAPT
SCHEMBL10731682 0.91 MEN1 (0.50) MEN1THRBHTTKMT2AMAPT
SCHEMBL537919 0.91 MEN1 (0.50) MEN1THRBHTTKMT2AMAPT
SCHEMBL21126403 0.91 MEN1 (0.50) MEN1THRBHTTKMT2AMAPT
SCHEMBL9549560 0.91 THRB (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL9549581 0.91 THRB (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL6124099 0.91 BCHE (0.43) MEN1THRBHTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9511008-B2 Conditioning composition for keratin fibres and its use KAO GERMANY GMBH (DE) 2016-12-06 US claimed
US-12605325-B2 Hair styling compositions for improving the elongation of hair curls L'OREAL (FR) 2026-04-21 US disclosed
US-12599546-B2 Hair treatment compositions, kits thereof, and methods thereof L'OREAL (FR) 2026-04-14 US disclosed
US-12589065-B2 Hair care system, hair care method and use of a hair care system L'OREAL (FR) 2026-03-31 US disclosed
US-12551422-B2 Compositions and methods for styling the hair L'ORÉAL (FR) 2026-02-17 US disclosed
US-20260000583-A1 COSMETIC KIT WITH A CLEANSING STICK, DISPENSING CONTAINER, AND CUTTING DEVICE L'OREAL (FR) 2026-01-01 US disclosed
US-20250367104-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN L'OREAL (FR) 2025-12-04 US disclosed
US-20250367103-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN L'OREAL (FR) 2025-12-04 US disclosed
EP-4633589-A1 HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER L'OREAL (FR) 2025-10-22 EP disclosed
US-20250302716-A1 HAIR TREATMENT SERUM AND METHOD OF USE L'OREAL (FR) 2025-10-02 US disclosed
WO-2010046077-A2 COLOURING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
WO-2010046080-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
EP-2177204-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed
EP-2177205-A1 Composition for the permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed
WO-2010025894-A2 CONDITIONING COMPOSITION FOR HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-03-11 WO disclosed
EP-2161016-A1 Conditioning composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-03-10 EP disclosed
EP-0176059-B1 PROCESS FOR THE MANUFACTURE OF LAKING PRODUCTS WITH IMPROVED APPLICATION PROPERTIES BASF Aktiengesellschaft (DE) 1991-11-27 EP disclosed
US-4664715-A Preparation of lakes having improved performance characteristics BASF AKTIENGESELLSCHAFT (DE) 1987-05-12 US disclosed
EP-0176059-A2 Process for the manufacture of laking products with improved application properties BASF Aktiengesellschaft (DE) 1986-04-02 EP disclosed
US-4456485-A PRECIPITATION IN PRESENCE OF AMINE, PHOSPHORIC OR SULFONIC ACID ESTER, ETHYLENE OXIDE ADDUCTS, OR POLYPROPYLENE GLYCOL OR COPOLYMERS THEREOF BASF WYANDOTTE CORPORATION (US) 1984-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367104-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN CUTA, DSG1, POLG MEN1 3901/4885THRB 4825/4885HTT 3708/4885
US-12605325-B2 Hair styling compositions for improving the elongation of hair curls SGMS1, SGMS2, SGPL1 MEN1 2163/4885THRB 960/4885HTT 223/4885
US-12551422-B2 Compositions and methods for styling the hair DPM1, PIK3C3, SMURF1 MEN1 1030/4885THRB 1352/4885HTT 2447/4885
US-12589065-B2 Hair care system, hair care method and use of a hair care system ASH2L, ALG3, PLOD3 MEN1 1541/4885THRB 903/4885HTT 410/4885
US-12599546-B2 Hair treatment compositions, kits thereof, and methods thereof EBP, FHIT, BRDT MEN1 992/4885THRB 1055/4885HTT 145/4885
US-20260000583-A1 COSMETIC KIT WITH A CLEANSING STICK, DISPENSING CONTAINER, AND CUTTING DEVICE CUTA, PRKDC, PRKACG MEN1 3266/4885THRB 4842/4885HTT 2442/4885
US-20250367103-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN CUTA, DSG1, POLG MEN1 3901/4885THRB 4825/4885HTT 3708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.