Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587272 | 0.92 | TYR (0.43) | HTTTYRTRPA1PTGS1CACNA1C | |
| SCHEMBL406972 | 0.89 | CHRNA7 (0.41) | ALDH1A1ALOX12ALOX5 | |
| SCHEMBL17226284 | 0.87 | IDO1 (0.43) | HTTTRPA1ALDH1A1IDO1 | |
| SCHEMBL11781825 | 0.87 | ADRB2 (0.50) | ALDH1A1HIF1AIDO1ADRB2 | |
| SCHEMBL18800689 | 0.86 | HCAR2 (0.47) | HCAR2TRPA1ALDH1A1ALOX12HIF1A | |
| SCHEMBL297137 | 0.86 | HCAR2 (0.47) | HCAR2TRPA1ALDH1A1ALOX12HIF1A | |
| SCHEMBL11785986 | 0.85 | CA1 (0.50) | PTGS1ALDH1A1ALOX5PTGS2AKR1C2 | |
| SCHEMBL9242079 | 0.83 | TSHR (0.47) | ESR1ESR2ALDH1A1IDO1AKR1C2 | |
| SCHEMBL9245803 | 0.83 | LMNA (0.44) | HTTTYRALDH1A1AKR1C2 | |
| SCHEMBL12090708 | 0.80 | LPL (0.44) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202386-A | Adhesion to polar material | AKZO NV (NL) | 1993-04-13 | — | — | US | disclosed |