SCHEMBL9549873

SCHEMBL9549873

CCC(C)c1cnc2nc(N)nc(N)c2c1C

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHFR P00374 8/20 0.48
SLC2A1 P11166 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27188510 0.75 DHFR (0.52) DHFRSLC2A1
SCHEMBL30092875 0.75 DHFR (0.52) DHFRSLC2A1
SCHEMBL8319768 0.75 DHFR (0.64) DHFRSLC2A1
Bromide SCHEMBL9542002 0.74 DHFR (0.63) DHFRSLC2A1
SCHEMBL9068396 0.72 DHFR (0.60) DHFRSLC2A1
SCHEMBL5462527 0.71 DHFR (0.58) DHFRSLC2A1
SCHEMBL10689192 0.69 DHFR (0.50) DHFRSLC2A1
SCHEMBL4222830 0.69 DHFR (0.47) DHFRSLC2A1
SCHEMBL26578140 0.68 HSP90AA1 (0.36) DHFR
SCHEMBL10465515 0.68 DHFR (0.74) DHFRSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5190760-A Drugs for bactericides and anthelmintics COOPERS ANIMAL HEALTH LIMITED (GB) 1993-03-02 US disclosed