SCHEMBL9550209

SCHEMBL9550209

CCCCCCNCCOc1ccc(Cl)c(Cl)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.51
BACE1 P56817 1/20 0.45
KMT2A Q03164 3/20 0.45
TP53 P04637 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
DRD2 P14416 2/20 0.43
DRD4 P21917 2/20 0.43
DRD3 P35462 2/20 0.43
S1PR2 O95136 1/20 0.42
S1PR1 P21453 1/20 0.42
S1PR3 Q99500 1/20 0.42
LPAR2 Q9HBW0 1/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
KDM4E B2RXH2 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9143231 0.79 KMT2A (0.56) ESR1BACE1KMT2ATSHRTDP1
SCHEMBL22138544 0.78 L3MBTL1 (0.43) KMT2ATP53CYP1A2CYP3A4CYP2D6
SCHEMBL9763250 0.78 ESR1 (0.60) ESR1KMT2ATP53DRD2DRD4
SCHEMBL9146021 0.74 SMN1; SMN2 (0.62) ESR1KMT2ATP53DRD2DRD4
SCHEMBL9618466 0.72 TP53 (0.69) ESR1KMT2ATP53CYP1A2CYP2D6
SCHEMBL9145426 0.72 ALDH1A1 (0.46) ESR1KMT2ATP53TSHRDRD2
SCHEMBL9618169 0.71 LMNA (0.58) ESR1KMT2ATDP1S1PR1ALDH1A1
SCHEMBL10881433 0.71 KMT2A (0.52) ESR1BACE1KMT2ACYP1A2CYP2D6
SCHEMBL12968231 0.70 GLA (0.49) BACE1TP53CYP1A2CYP3A4CYP2D6
SCHEMBL10881356 0.69 KMT2A (0.54) BACE1KMT2ACYP1A2CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5058969-A None JP disclosed
JP-H0558969-A PHENOXYETHYLAMINE AND AGRICULTURAL/HORTICULTURAL BACTERICIDE MITSUBISHI GAS CHEM CO INC 1993-03-09 JP disclosed