Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25660621 | 0.80 | LMNA (0.38) | LMNAALKBH5SUCNR1EGLN1HSD17B10 | |
| SCHEMBL21085153 | 0.78 | HSD17B10 (0.38) | LMNAALKBH5SUCNR1EGLN1HSD17B10 | |
| SCHEMBL9170323 | 0.76 | LMNA (0.44) | LMNAALKBH5SUCNR1EGLN1HSD17B10 | |
| SCHEMBL16512741 | 0.74 | SLC6A12 (0.50) | ALOX5SLC6A12SLC6A11SLC6A13GRM5 | |
| SCHEMBL16499292 | 0.74 | SLC6A12 (0.50) | ALOX5SLC6A12SLC6A11SLC6A13GRM5 | |
| SCHEMBL2466288 | 0.74 | SLC6A12 (0.50) | ALOX5SLC6A12SLC6A11SLC6A13GRM5 | |
| SCHEMBL23454432 | 0.73 | — | — | |
| SCHEMBL21085164 | 0.72 | HSD17B10 (0.34) | LMNAHSD17B10KMT2ATDP1TSHR | |
| SCHEMBL8158503 | 0.72 | ALDH1A1 (0.43) | LMNAALKBH5SUCNR1EGLN1HSD17B10 | |
| SCHEMBL9183918 | 0.72 | KDM4E (0.41) | LMNAHSD17B10KMT2ATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0484381-A1 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |