Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | DNTT | P04053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951083 | 0.79 | TP53 (0.41) | TP53CYP3A4CTSKNAAA | |
| SCHEMBL258793 | 0.79 | ALDH1A1 (0.36) | CYP3A4CTSKDNTT | |
| SCHEMBL7937163 | 0.79 | TLR4 (0.39) | CYP3A4NAAATSHRTLR4SPHK2 | |
| SCHEMBL9386943 | 0.75 | TP53 (0.37) | TP53CYP3A4 | |
| SCHEMBL1296622 | 0.74 | TSHR (0.47) | TP53CYP3A4NAAATSHR | |
| SCHEMBL21243334 | 0.74 | CYP1A2 (0.48) | TP53CYP3A4NAAAHTT | |
| SCHEMBL1471700 | 0.74 | DGKA (0.53) | TSHR | |
| SCHEMBL1296260 | 0.73 | NAAA (0.50) | TP53CYP3A4NAAATSHR | |
| SCHEMBL1296699 | 0.73 | NAAA (0.50) | TP53CYP3A4NAAATSHR | |
| SCHEMBL1296147 | 0.73 | NAAA (0.50) | TP53CYP3A4NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0484381-A1 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |