Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.33 |
| ▸ | CBR1 | P16152 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550451 | 0.82 | SLC6A3 (0.43) | ERAP1MAOBMAOAMEN1KMT2A | |
| SCHEMBL9550507 | 0.81 | ERAP1 (0.47) | ERAP1MAOBMAOAKDM4EMEN1 | |
| SCHEMBL9550484 | 0.81 | MAOA (0.47) | ERAP1MAOBMAOAMEN1LMNA | |
| SCHEMBL9550421 | 0.80 | ERAP1 (0.41) | ERAP1MAOBMAOALMNA | |
| SCHEMBL9368976 | 0.80 | NTRK1 (0.49) | ERAP1MAOAKDM4EMEN1KMT2A | |
| SCHEMBL9370300 | 0.79 | PTPN1 (0.47) | ERAP1MAPT | |
| SCHEMBL9367517 | 0.79 | HDAC3 (0.47) | ERAP1MAOBMAOAKDM4EMEN1 | |
| SCHEMBL9550466 | 0.78 | MAPT (0.34) | ERAP1KDM4ECBR1AKR1C3LMNA | |
| SCHEMBL9368059 | 0.78 | FASN (0.43) | ERAP1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9550495 | 0.77 | CYSLTR1 (0.49) | ERAP1MAOBMAOAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182295-A | Miticides, fungicides | ROUSSEL UCLAF (FR) | 1993-01-26 | — | — | US | claimed |