SCHEMBL9550495

SCHEMBL9550495

CO/C=C(/C(=O)OC)c1cccc2cc(-c3ccc(Oc4ccccc4)cc3)oc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 3/20 0.49
ERAP1 Q9NZ08 2/20 0.44
NTRK1 P04629 1/20 0.39
NTRK2 Q16620 1/20 0.39
MAOA P21397 2/20 0.39
MAOB P27338 1/20 0.39
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
DHODH Q02127 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
ABCB1 P08183 1/20 0.36
ABCC1 P33527 1/20 0.36
CYP1B1 Q16678 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550413 0.93 CYSLTR1 (0.41) CYSLTR1ERAP1MAOAMAOBDHODH
SCHEMBL9550507 0.91 ERAP1 (0.47) CYSLTR1ERAP1NTRK1NTRK2MAOA
SCHEMBL9550484 0.91 MAOA (0.47) CYSLTR1ERAP1MAOAMAOBALDH1A1
SCHEMBL9368976 0.90 NTRK1 (0.49) ERAP1NTRK1NTRK2MAOAALDH1A1
SCHEMBL9550451 0.88 SLC6A3 (0.43) ERAP1NTRK1NTRK2MAOAMAOB
SCHEMBL9550421 0.86 ERAP1 (0.41) ERAP1MAOAMAOBALDH1A1HPGD
SCHEMBL9367517 0.85 HDAC3 (0.47) ERAP1NTRK1NTRK2MAOAMAOB
SCHEMBL9550477 0.82 ADORA3 (0.43) ERAP1MAOAMAOBALDH1A1KDM4E
SCHEMBL9370300 0.81 PTPN1 (0.47) ERAP1ALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL9550481 0.80 ALDH1A1 (0.40) MAOAMAOBALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5182295-A Miticides, fungicides ROUSSEL UCLAF (FR) 1993-01-26 US disclosed