Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282582 | 0.86 | OPRM1 (0.48) | OPRM1OPRK1MTNR1AMTNR1BMAOA | |
| Hydrochloric Acid SCHEMBL29878326 | 0.85 | OPRM1 (0.47) | OPRM1OPRK1MTNR1AMTNR1BMAOA | |
| SCHEMBL2263418 | 0.84 | TDP1 (0.53) | OPRM1OPRK1MTNR1AMTNR1BEED | |
| SCHEMBL31425844 | 0.84 | TDP1 (0.53) | OPRM1OPRK1MTNR1AMTNR1BEED | |
| SCHEMBL5986566 | 0.83 | MTNR1A (0.49) | OPRM1OPRK1MTNR1AMTNR1BMAOA | |
| SCHEMBL9911545 | 0.80 | MTNR1A (0.47) | OPRM1OPRK1MTNR1AMTNR1BMAOA | |
| SCHEMBL31426029 | 0.76 | MTNR1A (0.47) | OPRM1OPRK1MTNR1AMTNR1BMAOB | |
| SCHEMBL3794946 | 0.76 | MTNR1A (0.51) | OPRM1OPRK1MTNR1AMTNR1BMAOA | |
| SCHEMBL5357479 | 0.76 | MAOB (0.47) | OPRM1OPRK1MTNR1AMTNR1BMAOA | |
| SCHEMBL27940164 | 0.76 | EED (0.46) | OPRM1OPRK1MTNR1AMTNR1BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194465-A | — | — | None | — | — | JP | disclosed |
| JP-H05194465-A | 2-AMINO-MONO-METHOXYCYCLOHEXYLAMIDES USEFUL AS ANALGESIC | WARNER LAMBERT CO | 1993-08-03 | — | — | JP | disclosed |
| EP-0552386-A1 | 2-Amino-3 or 6-methoxycyclohexyl amide derivatives | WARNER-LAMBERT COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5051428-A | 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics | WARNER-LAMBERT COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0372466-A2 | 2-Amino-4 or 5-methoxycyclohexyl amides useful as analgesics | WARNER-LAMBERT COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |