Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.46 |
| ▸ | EED | O75530 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986566 | 0.83 | MTNR1A (0.49) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| SCHEMBL31425844 | 0.81 | TDP1 (0.53) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| SCHEMBL2263418 | 0.81 | TDP1 (0.53) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| SCHEMBL1282582 | 0.80 | OPRM1 (0.48) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| SCHEMBL9550460 | 0.80 | OPRM1 (0.48) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| Hydrochloric Acid SCHEMBL29878326 | 0.79 | OPRM1 (0.47) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| SCHEMBL9911358 | 0.78 | GABRA1 (0.48) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| SCHEMBL31426029 | 0.77 | MTNR1A (0.47) | MTNR1AMTNR1BOPRM1OPRK1MAOB | |
| SCHEMBL3794946 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BOPRM1OPRK1EED | |
| SCHEMBL5987863 | 0.75 | HTR2A (0.44) | MTNR1AMTNR1BEEDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-7517998-B2 | Benzothiazole or benzothiazine derivative of dipyrido(2,3;b:2',3'-e) diazepin-6-one; viricide against human t-cell leukemia/lymphoma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2009-04-14 | — | — | US | disclosed |