Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114400 | 0.91 | CA2 (0.69) | CA2POLBATMKDM4EHTR7 | |
| SCHEMBL1034882 | 0.91 | CA2 (0.69) | CA2POLBATMKDM4EHTR7 | |
| Hydrochloric Acid SCHEMBL10772018 | 0.89 | CA2 (0.67) | CA2POLBATMKDM4EHTR7 | |
| SCHEMBL19409880 | 0.87 | ATM (0.70) | CA2POLBATMKDM4EALDH1A1 | |
| SCHEMBL29535675 | 0.87 | ATM (0.70) | CA2POLBATMKDM4EALDH1A1 | |
| SCHEMBL44393 | 0.87 | ATM (0.70) | CA2POLBATMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9726669 | 0.85 | ATM (0.68) | CA2POLBATMKDM4EALDH1A1 | |
| SCHEMBL1251841 | 0.79 | CALM1 (0.58) | CA2POLBATMKDM4EHTR7 | |
| SCHEMBL27925729 | 0.79 | HTR7 (0.59) | CA2POLBATMKDM4EHTR7 | |
| SCHEMBL8485615 | 0.79 | GAA (0.72) | CA2POLBATMKDM4EHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569380-A1 | ACRIDINE DERIVATIVES. | GLAXO LAB SA (FR) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012132-A1 | ACRIDINE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1992-07-23 | — | — | WO | disclosed |