Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933335 | 0.74 | MAPK1 (0.61) | POLBMAPK1HSD17B10MAOBMAOA | |
| SCHEMBL2067883 | 0.74 | — | — | |
| SCHEMBL16568924 | 0.74 | — | — | |
| SCHEMBL5761914 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL5832199 | 0.69 | CDK1 (0.34) | HSD17B10CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL446036 | 0.69 | — | — | |
| SCHEMBL12483353 | 0.68 | — | — | |
| SCHEMBL5596934 | 0.67 | LMNA (0.43) | MAOBMAOA | |
| SCHEMBL690812 | 0.67 | MAPK1 (1.00) | POLBMAPK1HSD17B10MAOBMAOA | |
| SCHEMBL6438241 | 0.66 | KDM4E (0.40) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569384-A1 | FUNGICIDES. | ZENECA LTD (GB) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992013830-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1992-08-20 | — | — | WO | disclosed |