SCHEMBL9550880

SCHEMBL9550880

[N-]=[N+]=C1Cc2ccccc2C(S(=O)(=O)O)=C1S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.40
CES1 P23141 2/20 0.38
BCHE P06276 1/20 0.38
ALDH1A1 P00352 4/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 1/20 0.37
RNASEH1 O60930 1/20 0.33
MIF P14174 5/20 0.32
ADRA2A P08913 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
SLC6A4 P31645 1/20 0.32
HTR2B P41595 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MAOB P27338 1/20 0.32
SRD5A2 P31213 1/20 0.32
TDP2 O95551 1/20 0.32
CASP3 P42574 1/20 0.32
CASP7 P55210 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10398242 0.88 MAOA (0.38) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL1501177 0.77 MAOA (0.37) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL11757070 0.76 CES1 (0.57) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL17144667 0.75 MAOA (0.59) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL30311915 0.74 MAOA (0.57) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL887974 0.74 MAOA (0.57) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL8719618 0.71 MAOA (0.41) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL9243514 0.71 MAOA (0.40) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL8598299 0.70 MAOA (0.39) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL9550899 0.69 SMN1; SMN2 (0.34) TDP2MEN1KMT2ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5231223-A PROCESS FOR THE ARYLATION OF OLEFINS BAYER AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed