Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076780 | 0.75 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRLMNAHSP90AA1MAPT | |
| SCHEMBL8076772 | 0.75 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRLMNAHSP90AA1MAPT | |
| SCHEMBL8065777 | 0.71 | PGAM1 (0.38) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL9245580 | 0.70 | TSHR (0.31) | SMN1; SMN2TSHR | |
| SCHEMBL6015231 | 0.70 | PTPN1 (0.41) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL11797393 | 0.70 | MAPT (0.52) | SMN1; SMN2TSHRLMNAHSP90AA1MAPT | |
| SCHEMBL11650825 | 0.69 | PTPN1 (0.40) | SMN1; SMN2TSHRLMNAMAPTHIF1A | |
| SCHEMBL9550880 | 0.69 | MAOA (0.40) | SMN1; SMN2TSHRLMNATDP2MEN1 | |
| SCHEMBL8936666 | 0.69 | MEN1 (0.60) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL482108 | 0.67 | MEN1 (0.38) | SMN1; SMN2TSHRLMNAHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5231223-A | PROCESS FOR THE ARYLATION OF OLEFINS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |