Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | CCKAR | P32238 | 2/20 | 0.44 |
| ▸ | CCKBR | P32239 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335662 | 0.91 | CTSS (0.54) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL7351751 | 0.91 | CTSS (0.54) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL9876266 | 0.91 | CTSS (0.54) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL9551282 | 0.91 | CTSS (0.54) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL9551333 | 0.85 | ALDH1A1 (0.44) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL9551279 | 0.84 | HSP90AA1 (0.45) | MAPTALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL10420805 | 0.84 | CTSS (0.54) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL9551311 | 0.84 | REN (0.64) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL23598225 | 0.84 | ACE (0.57) | CTSSCTSKCTSLCTSBREN | |
| Bromide SCHEMBL9551342 | 0.84 | ALDH1A1 (0.47) | POLBALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202312-A | Antiarthritic agents, antiallergens, antidiabetic agents | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0372818-A2 | Imidazole-containing peptide and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |