Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 11/20 | 0.50 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221159 | 1.00 | DUT (0.50) | DUTTYMPHSP90AA1RNASE1MEN1 | |
| SCHEMBL3925356 | 1.00 | DUT (0.50) | DUTTYMPHSP90AA1RNASE1MEN1 | |
| SCHEMBL29722701 | 0.88 | DUT (0.54) | DUTTYMPHSP90AA1RNASE1P2RY12 | |
| SCHEMBL5475154 | 0.85 | RNASE1 (0.53) | RNASE1 | |
| SCHEMBL5489355 | 0.85 | RNASE1 (0.53) | RNASE1 | |
| SCHEMBL5475148 | 0.85 | RNASE1 (0.53) | RNASE1 | |
| SCHEMBL30976656 | 0.85 | RNASE1 (0.53) | RNASE1 | |
| SCHEMBL5489351 | 0.85 | RNASE1 (0.53) | RNASE1 | |
| SCHEMBL9810769 | 0.85 | TK1 (0.43) | TYMPRNASE1 | |
| SCHEMBL9810774 | 0.85 | TK1 (0.43) | TYMPRNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190926-A | HIV virus | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5159067-A | 5'-Diphosphohexose nucleoside pharmaceutical compositions | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC. (US) | 1992-10-27 | — | — | US | disclosed |
| US-5145840-A | Treatment of virac and bacterial infections; aids | BURROUGHS WELLCOME CO. (US) | 1992-09-08 | — | — | US | disclosed |
| US-5118672-A | Microbiocides, viricides, bactericides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) | 1992-06-02 | — | — | US | disclosed |
| US-5064946-A | 3-azido-2,3-dideoxy-B-D-erythro-pentofuranosyl derivatives of 4(1H)-pyrimidinones; antiretroviral, anti-AIDS | BURROUGHS WELLCOME CO. (US) | 1991-11-12 | — | — | US | disclosed |
| WO-1991000867-A1 | 5'-DIPHOSPHOHEXOSE NUCLEOSIDE PHARMACEUTICAL COMPOSITIONS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0301064-A1 | 3'-AZIDO-2',3'-DIDEOXYURIDINE ANTI-RETROVIRAL COMPOSITION. | CHU CHUNG K (US) | 1989-02-01 | — | — | EP | disclosed |
| WO-1988005657-A1 | 3'-AZIDO-2',3'-DIDEOXYURIDINE ANTI-RETROVIRAL COMPOSITION | CHU CHUNG K (US) | 1988-08-11 | — | — | WO | disclosed |
| EP-0217580-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-04-08 | — | — | EP | disclosed |