SCHEMBL95535

SCHEMBL95535

CC(C)CCCC(C)CCCC(C)CCBr

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.68
BLM P54132 1/20 0.48
PTPN1 P18031 3/20 0.42
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
PTPN2 P17706 1/20 0.32
CDC25B P30305 1/20 0.32
FNTA P49354 1/20 0.31
PGGT1B P53609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757747 1.00 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL996547 1.00 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL996546 1.00 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL95650 1.00 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL2735605 1.00 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL10405962 1.00 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL14658031 0.97 LMNA (0.65) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL16690502 0.92 LMNA (0.65) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL10844984 0.89 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL10535023 0.89 LMNA (0.68) LMNABLMPTPN1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3296306-B1 BASE-PROTECTED OLIGONUCLEOTIDE AJINOMOTO KK (JP) 2022-11-09 EP disclosed
EP-2816053-B1 BASE-PROTECTED OLIGONUCLEOTIDE AJINOMOTO KK (JP) 2021-03-24 EP disclosed
CN-106977567-B Oligonucleotide with protected base moiety 味之素株式会社 2021-02-02 CN disclosed
CN-107011132-B Aromatic compound containing branched chain 味之素株式会社 2020-11-10 CN disclosed
CN-107011131-B Aromatic compound containing branched chain 味之素株式会社 2020-11-10 CN disclosed
EP-2612845-B1 AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH AJINOMOTO KK (JP) 2020-08-05 EP disclosed
EP-2612845-B1 AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH AJINOMOTO KK (JP) 2020-08-05 EP disclosed
US-10711033-B2 Branched chain-containing aromatic compound AJINOMOTO CO., INC. (JP) 2020-07-14 US disclosed
CN-106220482-B Aromatic compound containing branched chain 味之素株式会社 2020-01-07 CN disclosed
US-10290809-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-05-14 US disclosed
US-6500892-B1 SATURATED ISOPRENE OLIGOMER BONDED TO A POLAR GROUP, QUATERNARY AMMONIUM BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-12-31 US disclosed
EP-1242359-A2 INTERCALATED CLAY MATERIAL USEFUL FOR MAKING ALPHA-OLEFIN POLYMER NANOCOMPOSITES AND INTERCALANT COMPOUND USED THEREIN Basell Poliolefine Italia S.p.A. (IT) 2002-09-25 EP disclosed
WO-2001096237-A2 INTERCALATED CLAY MATERIAL USEFUL FOR MAKING ALPHA-OLEFIN POLYMER NANOCOMPOSITES AND INTERCALANT COMPOUND USED THEREIN BASELL TECHNOLOGY COMPANY B.V. (US) 2001-12-20 WO disclosed
US-4904823-A Hydroquinone derivatives and a process for their preparation HOFFMANN-LA ROCHE INC. (US) 1990-02-27 US disclosed
US-4824972-A Hydroquinone derivatives HOFFMANN-LAROCHE INC. (US) 1989-04-25 US disclosed
US-4743696-A Hydroquinone derivatives and a process for their preparation HOFFMANN-LA ROCHE INC. (US) 1988-05-10 US disclosed
US-4709055-A (Alkoxy-methyl)-phenyl-methyl-epoxybutanes HOFFMANN-LA ROCHE INC. (US) 1987-11-24 US disclosed
US-4689427-A Hydroquinone derivatives useful in the production of vitamin E HOFFMANN-LA ROCHE INC. (US) 1987-08-25 US disclosed
US-4675421-A Hydroquinone derivatives and a process for their preparation HOFFMANN-LA ROCHE INC. (US) 1987-06-23 US disclosed
US-4582919-A Process for the manufacture of optically active compounds HOFFMANN-LA ROCHE INC. (US) 1986-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711033-B2 Branched chain-containing aromatic compound VIP, IAPP, BCAT1 LMNA 2252/4885BLM 2109/4885PTPN1 3937/4885
US-10290809-B2 Macromolecular compound EXOSC4, TRPC6, MRPS22 LMNA 3835/4885BLM 567/4885PTPN1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.