Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731175 | 0.94 | LTA4H (0.66) | LTA4HALOX5SIGMAR1SMN1; SMN2THRA | |
| SCHEMBL822621 | 0.89 | LTA4H (0.60) | LTA4HALOX5SIGMAR1THRATHRB | |
| SCHEMBL9554296 | 0.88 | ALOX5 (0.69) | LTA4HALOX5SIGMAR1SMN1; SMN2THRA | |
| SCHEMBL6839565 | 0.86 | KCNH2 (0.64) | LTA4HALOX5SMN1; SMN2TDP1FDPS | |
| SCHEMBL9554159 | 0.86 | LTA4H (0.51) | LTA4HALOX5SIGMAR1SMN1; SMN2THRA | |
| SCHEMBL1303146 | 0.85 | LTA4H (0.62) | LTA4HALOX5SMN1; SMN2 | |
| SCHEMBL260297 | 0.84 | ALOX5 (0.76) | ALOX5SMN1; SMN2TDP1 | |
| SCHEMBL25801191 | 0.84 | LTA4H (0.61) | LTA4HALOX5SIGMAR1TDP1 | |
| SCHEMBL6328999 | 0.83 | ALOX5 (0.69) | LTA4HALOX5TDP1 | |
| Hydrochloric Acid SCHEMBL27794216 | 0.83 | ALOX5 (0.74) | ALOX5SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190930-A | Calcium metabolism disorder | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5110807-A | Calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |