Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.45 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.45 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554286 | 0.86 | LTA4H (0.67) | LTA4HALOX5SMN1; SMN2THRATHRB | |
| SCHEMBL27469498 | 0.85 | ALOX5 (0.56) | ALOX5CYP4F2CYP4A11CYP4Z1CYP4F11 | |
| SCHEMBL4956699 | 0.84 | CYP4Z1 (0.56) | ALOX5CYP4F2CYP4A11CYP4Z1CYP4F11 | |
| SCHEMBL7420660 | 0.82 | CYP4Z1 (0.54) | ALOX5CYP4F2CYP4A11CYP4Z1CYP4F11 | |
| SCHEMBL2412884 | 0.82 | CYP4F2 (0.67) | ALOX5CYP4F2CYP4A11CYP4Z1NAMPT | |
| Hydrochloric Acid SCHEMBL9554629 | 0.81 | LTA4H (0.48) | LTA4HSMN1; SMN2ALDH1A1LMNASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7420658 | 0.81 | CYP4Z1 (0.53) | ALOX5CYP4F2CYP4A11CYP4Z1CYP4F11 | |
| SCHEMBL9731175 | 0.81 | LTA4H (0.66) | LTA4HALOX5SMN1; SMN2THRATHRB | |
| SCHEMBL7380546 | 0.80 | ALOX5 (0.48) | ALOX5CYP4F2CYP4A11CYP4Z1CYP4F11 | |
| SCHEMBL11585892 | 0.75 | CYP4F2 (0.50) | LTA4HALOX5CYP4F2CYP4A11CYP4Z1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190930-A | Calcium metabolism disorder | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5110807-A | Calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |