SCHEMBL955526

SCHEMBL955526

CC(C)(C)OC(=O)N[C@@H](CCOCc1ccccc1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.74
PPARG P37231 4/20 0.67
CTSS P25774 4/20 0.60
ACE P12821 1/20 0.56
CTSK P43235 4/20 0.53
FOLH1 Q04609 1/20 0.52
PPARD Q03181 2/20 0.52
CTSL P07711 1/20 0.52
CTSB P07858 1/20 0.52
KLK7 P49862 2/20 0.50
KLK5 Q9Y337 2/20 0.50
SYK P43405 1/20 0.48
ATM Q13315 1/20 0.48
PTPN1 P18031 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312604 1.00 PPARA (0.74) PPARAPPARGCTSSACECTSK
SCHEMBL955527 1.00 PPARA (0.74) PPARAPPARGCTSSACECTSK
SCHEMBL7442052 0.93 PPARA (0.71) PPARAPPARGCTSSACECTSK
SCHEMBL7405992 0.93 PPARA (0.71) PPARAPPARGCTSSACECTSK
SCHEMBL27897229 0.93 PPARA (0.71) PPARAPPARGCTSSACECTSK
SCHEMBL8615711 0.91 PPARA (0.69) PPARAPPARGCTSSACECTSK
SCHEMBL3348658 0.90 PPARA (0.64) PPARAPPARGCTSSACECTSK
SCHEMBL3348663 0.90 PPARA (0.64) PPARAPPARGCTSSACECTSK
SCHEMBL11901546 0.90 PPARA (0.64) PPARAPPARGCTSSACECTSK
SCHEMBL20899650 0.90 PPARA (0.82) PPARAPPARGCTSSACECTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630512-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2026-05-19 US disclosed
EP-4711368-A1 AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-03-18 EP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-3600451-B1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2025-12-24 EP disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
US-12202799-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2025-01-21 US disclosed
WO-2024251275-A1 AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF 成都麻沸散医药科技有限公司 2024-12-12 WO disclosed
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2024-12-12 US disclosed
CN-119101054-A Azepine compound, and composition and application thereof 成都麻沸散医药科技有限公司 2024-12-10 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-5741792-A ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-04-21 US disclosed
EP-0820445-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 1998-01-28 EP disclosed
US-5583146-A Heterocyclic thrombin inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-10 US disclosed
WO-1996030343-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1996-10-03 WO disclosed
EP-0623596-A1 N-acylpyrrolidines or N-acylpiperidines having a guanidinyl- or amidinyl-substituted side chain as thrombin inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1994-11-09 EP disclosed
EP-0266950-B1 Nor-statine and nor-cyclostatine polypeptides PFIZER (US) 1993-12-29 EP disclosed
US-5034376-A Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1991-07-23 US disclosed
US-4935405-A Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1990-06-19 US disclosed
US-4814342-A Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1989-03-21 US disclosed
EP-0266950-A2 Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1988-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 PPARA 2794/4885PPARG 3131/4885CTSS 4022/4885
US-12202799-B2 Agents for differentiating stem cells and treating cancer MCL1, CD44, CRABP2 PPARA 1349/4885PPARG 521/4885CTSS 3193/4885
US-12630512-B2 Agents for differentiating stem cells and treating cancer MCL1, POU2F1, NES PPARA 3314/4885PPARG 1786/4885CTSS 3011/4885
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 PPARA 1349/4885PPARG 521/4885CTSS 3193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.