Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8865857 | 0.89 | MME (0.51) | L3MBTL1FNTAFNTBMMEANPEP | |
| SCHEMBL8333462 | 0.84 | L3MBTL1 (0.48) | L3MBTL1FNTAFNTBHTTCASP1 | |
| SCHEMBL8333460 | 0.84 | L3MBTL1 (0.48) | L3MBTL1FNTAFNTBHTTCASP1 | |
| SCHEMBL9555329 | 0.83 | MME (0.53) | FNTAFNTBMMEANPEPPPID | |
| SCHEMBL9555177 | 0.83 | MME (0.53) | FNTAFNTBMMEANPEPPPID | |
| Hydrochloric Acid SCHEMBL9555452 | 0.82 | MME (0.52) | FNTAFNTBMMEANPEPPPID | |
| SCHEMBL9555216 | 0.82 | MME (0.62) | FNTAFNTBMMEANPEP | |
| Hydrochloric Acid SCHEMBL9555453 | 0.82 | MME (0.52) | FNTAFNTBMMEANPEPPPID | |
| SCHEMBL9555215 | 0.82 | MME (0.62) | FNTAFNTBMMEANPEP | |
| SCHEMBL29732398 | 0.81 | LTA4H (0.56) | FNTAFNTBMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238922-A | Anticancer agents | MERCK & CO., INC. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0535731-A2 | Inhibitors of farnesyl protein transferase | MERCK & CO. INC. (US) | 1993-04-07 | — | — | EP | disclosed |