Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557503 | 0.94 | CES2 (0.47) | OPRM1OPRD1OPRK1NPC1L3MBTL1 | |
| SCHEMBL9557442 | 0.94 | ALDH1A1 (0.45) | OPRM1OPRD1OPRK1ALDH1A1L3MBTL1 | |
| SCHEMBL9557370 | 0.94 | CES2 (0.47) | OPRM1OPRD1OPRK1NPC1L3MBTL1 | |
| SCHEMBL9558150 | 0.94 | ALDH1A1 (0.45) | OPRM1OPRD1OPRK1ALDH1A1L3MBTL1 | |
| SCHEMBL9557764 | 0.93 | OPRM1 (0.40) | OPRM1OPRD1OPRK1NPC1ALDH1A1 | |
| SCHEMBL9557390 | 0.92 | OPRM1 (0.40) | OPRM1OPRD1OPRK1NPC1ALDH1A1 | |
| SCHEMBL9557564 | 0.90 | MCHR1 (0.43) | OPRM1OPRD1OPRK1POLBCES2 | |
| SCHEMBL9558080 | 0.90 | TSHR (0.48) | OPRM1OPRD1OPRK1ALDH1A1MEN1 | |
| SCHEMBL9557729 | 0.89 | ALDH1A1 (0.49) | OPRM1OPRD1OPRK1ALDH1A1MEN1 | |
| SCHEMBL9557504 | 0.87 | HPGD (0.51) | NPC1ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |