Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557171 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9825403 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9557291 | 0.71 | TP53 (0.38) | SMN1; SMN2ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9558110 | 0.69 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1GAAHPGDLMNA | |
| SCHEMBL9557674 | 0.69 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1GAAHPGDLMNA | |
| SCHEMBL18992044 | 0.68 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9557846 | 0.66 | CTSD (0.46) | SMN1; SMN2ALDH1A1GAALMNACTSD | |
| Isobutanol SCHEMBL28843629 | 0.64 | CTSD (0.49) | SMN1; SMN2ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL25068818 | 0.63 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL7761933 | 0.63 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |