Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557171 | 0.80 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2GAACTSDRAB9A | |
| SCHEMBL9557488 | 0.78 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2GAACTSDRAB9A | |
| SCHEMBL9825708 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAACTSDRAB9A | |
| SCHEMBL10721229 | 0.72 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2GAACTSDRAB9A | |
| SCHEMBL9714340 | 0.71 | ABCB1 (0.49) | SMN1; SMN2HPGD | |
| SCHEMBL18992044 | 0.69 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAACTSDRAB9A | |
| SCHEMBL9714639 | 0.67 | POLB (0.63) | — | |
| SCHEMBL9714483 | 0.67 | ABCB1 (0.54) | ALDH1A1GAALMNAKDM4EL3MBTL1 | |
| SCHEMBL9824979 | 0.67 | CTSD (0.47) | ALDH1A1SMN1; SMN2GAACTSDRAB9A | |
| SCHEMBL5058440 | 0.67 | HPGD (0.64) | SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |