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Sugi Predict / Compounds / SCHEMBL9557502

SCHEMBL9557502

SCHEMBL9557502

CCN(C(=O)c1ccccc1Cl)N(C(=O)c1ccc(Cl)c(Cl)c1)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.45
▸ TP53 P04637 1/20 0.45
▸ ABCB1 P08183 2/20 0.44
▸ SLC6A2 P23975 1/20 0.43
▸ SLC6A4 P31645 1/20 0.43
▸ SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9557515 0.88 TSHR (0.52) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL9557487 0.88 TSHR (0.47) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL9557481 0.87 TP53 (0.52) TP53ABCB1
SCHEMBL9557722 0.87 TP53 (0.54) TP53ABCB1
SCHEMBL9557371 0.84 ABCB1 (0.46) ABCB1SLC6A2SLC6A4SLC6A3
SCHEMBL9558080 0.84 TSHR (0.48) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL9557739 0.83 TP53 (0.43) TP53ABCB1
SCHEMBL9558149 0.82 TSHR (0.47) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL9557470 0.82 TP53 (0.47) TP53ABCB1
SCHEMBL9557645 0.82 TP53 (0.52) TP53ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225443-A Lepidotera and Coleoptera insecticides to protect plants ROHM AND HAAS COMPANY (US) 1993-07-06 — — US disclosed
EP-0245950-A2 Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1987-11-19 — — EP disclosed
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