Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558080 | 0.95 | TSHR (0.48) | TSHRHSP90AA1HSP90AB1OPRM1OPRD1 | |
| SCHEMBL9557487 | 0.93 | TSHR (0.47) | TSHRHSP90AA1HSP90AB1OPRM1OPRD1 | |
| SCHEMBL9558149 | 0.93 | TSHR (0.47) | TSHRHSP90AA1HSP90AB1OPRM1OPRD1 | |
| SCHEMBL9557502 | 0.88 | TSHR (0.45) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9557192 | 0.83 | OPRM1 (0.45) | TSHROPRM1OPRD1OPRK1KMT2A | |
| SCHEMBL9557513 | 0.83 | LMNA (0.43) | TSHRHSP90AA1HSP90AB1OPRM1OPRD1 | |
| SCHEMBL9558002 | 0.82 | TSHR (0.44) | TSHRHSP90AA1HSP90AB1OPRM1OPRD1 | |
| SCHEMBL9557554 | 0.81 | ALDH1A1 (0.53) | OPRK1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL9557416 | 0.80 | TSHR (0.46) | TSHRHSP90AA1HSP90AB1SLC6A2SLC6A4 | |
| SCHEMBL9557764 | 0.80 | OPRM1 (0.40) | HSP90AA1HSP90AB1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |