Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557515 | 0.93 | TSHR (0.52) | TSHRKMT2ALMNACYP2D6OPRM1 | |
| SCHEMBL9558080 | 0.91 | TSHR (0.48) | TSHRKMT2AMAPTMEN1LMNA | |
| SCHEMBL9557513 | 0.90 | LMNA (0.43) | TSHRKMT2AMAPTMEN1LMNA | |
| SCHEMBL9558149 | 0.90 | TSHR (0.47) | TSHRKMT2AMAPTMEN1LMNA | |
| SCHEMBL9557502 | 0.88 | TSHR (0.45) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9558150 | 0.87 | ALDH1A1 (0.45) | MAPTOPRM1OPRD1OPRK1PPARG | |
| SCHEMBL9557442 | 0.87 | ALDH1A1 (0.45) | MAPTOPRM1OPRD1OPRK1PPARG | |
| SCHEMBL9557521 | 0.86 | ALDH1A1 (0.49) | MAPTCYP3A4CYP2C9OPRM1OPRD1 | |
| SCHEMBL9557562 | 0.86 | ALDH1A1 (0.50) | MAPTCYP3A4CYP2C9CYP2C19OPRK1 | |
| SCHEMBL9558131 | 0.86 | ALDH1A1 (0.50) | MAPTCYP3A4CYP2C9CYP2C19OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |