Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557515 | 0.93 | TSHR (0.52) | TSHROPRM1OPRD1OPRK1HSP90AA1 | |
| SCHEMBL9558080 | 0.91 | TSHR (0.48) | TSHROPRM1OPRD1OPRK1HSP90AA1 | |
| SCHEMBL9557487 | 0.90 | TSHR (0.47) | TSHROPRM1OPRD1OPRK1HSP90AA1 | |
| SCHEMBL9557418 | 0.88 | MAPT (0.40) | OPRM1OPRD1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9557370 | 0.87 | CES2 (0.47) | OPRM1OPRD1OPRK1LMNAKMT2A | |
| SCHEMBL9557503 | 0.87 | CES2 (0.47) | OPRM1OPRD1OPRK1LMNAKMT2A | |
| SCHEMBL9557742 | 0.86 | CNR2 (0.39) | OPRM1OPRD1HSP90AA1HSP90AB1LMNA | |
| SCHEMBL9557257 | 0.85 | ALDH1A1 (0.47) | OPRK1SLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL9557357 | 0.83 | HPGD (0.55) | HDAC8HDAC6KMT2AMEN1CYP3A4 | |
| SCHEMBL9557579 | 0.83 | TSHR (0.41) | TSHROPRM1OPRD1OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |