Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557119 | 0.91 | TSHR (0.52) | TSHRMAPK1KMT2AABCB1ERCC5 | |
| SCHEMBL9557931 | 0.91 | TSHR (0.52) | TSHRMAPK1KMT2AABCB1ERCC5 | |
| SCHEMBL9557349 | 0.89 | TSHR (0.47) | TSHRMAPK1KMT2AABCB1HDAC1 | |
| SCHEMBL9557332 | 0.87 | TSHR (0.45) | TSHRMAPK1KMT2AABCB1HDAC1 | |
| SCHEMBL11213915 | 0.85 | TSHR (0.60) | TSHRMAPK1KMT2AERCC5FEN1 | |
| SCHEMBL9557605 | 0.83 | MEN1 (0.43) | KMT2AERCC5FEN1HDAC1TP53 | |
| SCHEMBL9557722 | 0.83 | TP53 (0.54) | ABCB1TP53 | |
| SCHEMBL9558221 | 0.81 | CTSD (0.45) | TSHRHDAC1HDAC6TP53HPGD | |
| SCHEMBL9557589 | 0.81 | OPRM1 (0.44) | TSHRMAPK1KMT2ATP53HPGD | |
| SCHEMBL9557556 | 0.79 | KMT2A (0.49) | TSHRMAPK1KMT2AABCB1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |