Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558035 | 0.92 | NPC1 (0.48) | CTSDOPRM1OPRD1NPC1MAPT | |
| SCHEMBL9557258 | 0.81 | CTSD (0.49) | CTSDABCG2NPC1MAPTNPSR1 | |
| SCHEMBL9557648 | 0.81 | TSHR (0.50) | HPGDTP53TSHRHDAC1HDAC6 | |
| SCHEMBL9557605 | 0.79 | MEN1 (0.43) | OPRM1OPRD1NPC1MAPTTP53 | |
| SCHEMBL9557722 | 0.79 | TP53 (0.54) | TP53LMNA | |
| SCHEMBL9557199 | 0.79 | KDM4E (0.48) | MAPTHPGDLMNATSHRKDM4E | |
| SCHEMBL9557438 | 0.79 | KMT2A (0.41) | OPRM1OPRD1NPC1HPGD | |
| SCHEMBL9557589 | 0.77 | OPRM1 (0.44) | OPRM1OPRD1MAPTNPSR1HPGD | |
| SCHEMBL30130383 | 0.77 | OPRM1 (0.56) | CTSDOPRM1OPRD1NPC1MAPT | |
| SCHEMBL812080 | 0.77 | OPRM1 (0.56) | CTSDOPRM1OPRD1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |