SCHEMBL9558237

SCHEMBL9558237

CC(C)(COCc1ccc(F)c(Oc2cccc(Cl)c2)c1)c1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.40
HTR2A P28223 4/20 0.40
KCNH2 Q12809 4/20 0.40
P2RX4 Q99571 4/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A3 Q01959 2/20 0.38
PKM P14618 1/20 0.35
RHEB Q15382 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAOB P27338 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PGGT1B P53609 1/20 0.34
HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10836788 0.91 L3MBTL1 (0.43) SLC6A4HTR2AKCNH2P2RX4L3MBTL1
SCHEMBL9029398 0.91 TTR (0.39) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL10853926 0.86 FFAR4 (0.39) SLC6A4KCNH2SLC6A2SLC6A3PKM
SCHEMBL9558421 0.86 HTR2A (0.41) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL10851466 0.86 ALDH1A1 (0.41) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL9557909 0.85 MEN1 (0.40) SLC6A4HTR2AKCNH2L3MBTL1MAOB
SCHEMBL9558336 0.85 SLC6A2 (0.38) SLC6A4KCNH2SLC6A2SLC6A3PKM
SCHEMBL9838544 0.84 SLC6A4 (0.37) SLC6A4HTR2AKCNH2MAOB
SCHEMBL10837117 0.83 NPC1 (0.38)
SCHEMBL10546882 0.83 SLC6A4 (0.39) SLC6A4HTR2AKCNH2P2RX4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed