Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557416 | 0.94 | TSHR (0.46) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9557559 | 0.90 | CYP3A4 (0.49) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9557579 | 0.90 | TSHR (0.41) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9557820 | 0.89 | TRPA1 (0.42) | TSHRCYP1A2CYP2C19MAPTALDH1A1 | |
| SCHEMBL9557219 | 0.85 | CYP2C19 (0.39) | TSHRCYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL9556950 | 0.84 | ALDH1A1 (0.43) | FLT1FLT4KDRCYP1A2CYP2D6 | |
| SCHEMBL9557624 | 0.84 | CES2 (0.51) | TSHRCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL9557392 | 0.84 | CES2 (0.51) | TSHRCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL9557635 | 0.84 | CES2 (0.49) | TSHRMEN1LMNAMAPTKMT2A | |
| SCHEMBL9557877 | 0.84 | CES2 (0.49) | TSHRMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |