Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557559 | 0.89 | CYP3A4 (0.49) | LMNASLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL9557513 | 0.84 | LMNA (0.43) | LMNASLC6A2SLC6A4SLC6A3CHRNA1 | |
| SCHEMBL9557635 | 0.83 | CES2 (0.49) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9557877 | 0.83 | CES2 (0.49) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8174989 | 0.83 | POLB (0.50) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9KMT2A | |
| SCHEMBL9557598 | 0.82 | ABCB1 (0.47) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9557381 | 0.82 | ABCB1 (0.47) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9557966 | 0.82 | CES2 (0.50) | LMNAMAPTALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL9557416 | 0.82 | TSHR (0.46) | LMNASLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL9557283 | 0.82 | CES2 (0.50) | LMNAMAPTALDH1A1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |