Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557820 | 0.89 | TRPA1 (0.42) | CES2CES1POLBPDK2 | |
| SCHEMBL9557173 | 0.87 | CYP1A1 (0.50) | CES2CES1PDK2 | |
| SCHEMBL9557467 | 0.87 | MEN1 (0.48) | CES2CES1POLB | |
| SCHEMBL9557392 | 0.84 | CES2 (0.51) | UTS2RCES2CES1POLB | |
| SCHEMBL9557624 | 0.84 | CES2 (0.51) | UTS2RCES2CES1POLB | |
| SCHEMBL9557635 | 0.84 | CES2 (0.49) | CES2CES1POLB | |
| SCHEMBL9557877 | 0.84 | CES2 (0.49) | CES2CES1POLB | |
| SCHEMBL9557219 | 0.82 | CYP2C19 (0.39) | CES2CES1POLBPDK2CNR2 | |
| SCHEMBL9557564 | 0.82 | MCHR1 (0.43) | CYP11B1CYP11B2UTS2RMCHR1CES2 | |
| SCHEMBL9557720 | 0.80 | ALDH1A1 (0.41) | MCHR1POLBPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |