Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557598 | 0.90 | ABCB1 (0.47) | POLBCYP3A4CYP2C9MAPTCYP2C19 | |
| SCHEMBL9557381 | 0.90 | ABCB1 (0.47) | POLBCYP3A4CYP2C9MAPTCYP2C19 | |
| SCHEMBL9557219 | 0.90 | CYP2C19 (0.39) | ACLYPOLBCYP3A4CYP2C9CYP1A2 | |
| SCHEMBL9557635 | 0.88 | CES2 (0.49) | POLBKMT2AMEN1LMNAMAPT | |
| SCHEMBL9557877 | 0.88 | CES2 (0.49) | POLBKMT2AMEN1LMNAMAPT | |
| SCHEMBL8174989 | 0.87 | POLB (0.50) | POLBCYP3A4CYP2C9KMT2A | |
| SCHEMBL9557629 | 0.87 | CNR1 (0.41) | ACLYCYP3A4CYP2C9MAPTCYP2C19 | |
| SCHEMBL9557427 | 0.85 | ALDH1A1 (0.48) | POLBCYP3A4CYP2C9MAPTCYP2C19 | |
| SCHEMBL9558223 | 0.84 | ABCB1 (0.48) | POLBCYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL9557559 | 0.83 | CYP3A4 (0.49) | POLBCYP3A4CYP2C9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |